Effects of silver nanoparticle/graphene oxide composite on the properties of polymethyl methacrylate base material <i>in vitro</i>

Polymethyl methacrylate (PMMA) has been widely used in stomatology to prepare denture bases. However, issues such as a porous structure and high water absorption rate facilitate bacterial growth. This study aimed synthesize silver nanoparticle/graphene oxide (AgNPs/GO) composites by the chemical reduction method, which was mixed with PMMA ball milling method improve antibacterial properties of PMMA. Scanning electron microscopy transmission showed that AgNPs were uniformly dispersed on GO sheets. AgNPs/GO composite investigated using x-ray diffraction. The modified AgNPs/GO/PMMA demonstrated enhanced against Streptococcus mutans based film adhesion test. Also, number bacteria decreased morphology changed increase mass fraction. Besides, improved mechanical confirmed friction contact angle tests. Moreover, did not induce cytotoxicity human gingival mesenchymal stem cells.